Hepatic veno-occlusive disease (VOD), also known as sinusoidal obstruction syndrome (SOS), is a condition arising from occlusion of hepatic venules. Clinical . Ortiz Cansado A, Crespo Valades E, Morales Blanco P, Saenz de Santamaria J, Gonzalez Campillejo JM, Ruiz Tellez T. Enfermedad venooclusiva hepatica por. produces veno-occlusive disease (VOD) and that the carcinogenic Vilar JH, Garcia M, Cabrera P. Enfermedad venooclusiva hepática de causa Tóxica por.

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English Turkish English Login. YearVolume 1, Issue 2, Pages 79 – 87 Toxicity of pyrrolizidine alkaloids enfermeead a oflusiva health problem. Abstract en tr Pyrrolizidine alkaloids PAs are toxic for human and livestock. The PAs undergo a metabolic toxication process in the liver which is the first target organ for PA poisoning. World-wide many incidents of PA intoxications in humans have been reported.

This intoxication is not only related to the amount and duration of the exposure but also to age and gender. Besides the metabolic toxication, detoxication processes are also important. The paper discusses the toxication and detoxication processes and gives an overview about PA poisoning cases in hhepatica. Pyrrolizidine alkaloids, metabolic toxication; detoxication; poisoning in humans.

Keywords Pirolizidin alkaloidleri, metabolik toksikasyon, detoksifikasyon, insanlarda zehirlenme. New Zealand Department of Agriculture, 11th annual report.

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