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Besvara 1 Visa diskussion. Via Nasdaq betalar man nu endast 3. Besvara 0 Visa diskussion. De de hette Maxim. The presentation aatl be webcast and available at: Daniel Teper, CEO of Immune, will provide an overview of the Companys business and expected milestones, including updates on the advancement of the two Phase 2 clinical trials with bertilimumab, a fully human monoclonal antibody targeting eotaxin-1, and information on the companys immuno-oncology pipeline.
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IMNP applies a personalized approach to treating and developing novel, highly targeted antibody therapeutics to improve the lives of patients with inflammatory diseases and cancer. Immunes lead product candidate, bertilimumab, is in phase II clinical development for moderate-to-severe ulcerative colitis as well as for bullous pemphigoid, an orphan autoimmune dermatological condition.
Other indications being considered for development include atopic dermatitis, Crohns disease, severe asthma and Atll an inflammatory liver disease.
Immune recently expanded its portfolio in immuno- dermatology with topical nano-formulated cyclosporine-A for the treatment of psoriasis and atopic dermatitis. Immunes oncology pipeline includes bispecific antibodies, nanotherapeutics, including NanomAbs rand several mid-to-late stage small molecules including Ceplene rAzixa r and Crolibulin r.
Immunes non-core pipeline includes AmiKet tma late clinical stage drug candidate for the treatment of neuropathic pain. For more information, visit Immunes website at www. Forward-Looking Statements This news release and any oral statements made with respect to the information contained in this news release contain forward-looking statements within the meaning of the Private Securities Litigation Reform Act of You are urged to consider statements that include the words “may,” “will,” “would,” “could,” “should,” “believes,” “estimates,” “projects,” “potential,” “expects,” “plans,” “anticipates,” “intends,” “continues,” “forecast,” “designed,” “goal” or the negative of those words or other comparable words to be uncertain and forward-looking.
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Such forward- looking statements include statements that express plans, anticipation, intent, contingency, goals, targets, future development and are otherwise not statements of historical fact. These statements are based on our current expectations and are subject to risks and uncertainties that could cause actual results or developments to be materially different from historical results or from any future results expressed or implied by such forward-looking statements.
Factors that may cause actual results or developments to differ materially include, but not limited to: These factors and other material risks are more fully discussed in our periodic reports, including our reports on Forms 8-K, Q and K and other filings with the U.
Securities and Exchange Commission. You are urged to carefully review and consider the disclosures found in our filings, which are available at www. You are cautioned not to place undue reliance on any forward-looking statements, any of which could turn out to be wrong due to inaccurate assumptions, unknown risks or uncertainties or other risk factors.
We expressly disclaim any obligation to publicly update any forward looking statements contained herein, whether as a result of new information, future events or otherwise, except as required by law.
We have decided to send this release to you again today, so it would not be overlooked during the onslaught of negative market news last week. We ahl that Immune Pharmaceuticals deserves your close attention and represents a great investment opportunity, especially during the current volatile market conditions. IMNP is a clinical stage development company researching and developing new and advanced therapies for the treatment of immune-inflammatory diseases and cancer.
Immune Therapeutics applies a highly personalized approach to disease treatment, developing novel and carefully targeted antibody therapeutics to improve the lives of patients. This approval allows the company to include U.
Immune is also starting to enroll patients in the Stl II clinical trial for moderate to severe ulcerative colitis, a serious immuno-inflammatory condition of the gastro-intestinal tract. The company recently expanded its portfolio lisan immuno-dermatology, topical Nano formulated Cyclosporine A CsA for the treatment of psoriasis and atopic dermatitis.
Besvara 2 Visa diskussion. Company scientists, in collaboration with a consortium of leading European research centers, developed a prototype HLA-DRx-CD5 bi-specific antibody construct consisting of tandemly arranged Fab fragments with direct anti-cancer effects in vitro, as well as anti-tumor activity and improved survival in a mouse xenograft model of disseminated leukemia. I noted in my article that this very interesting and somewhat “under the radar” news for Immune, a company that most investors follow because of the lead Phase 2 asset, Bertilimumab, for bullous pemphigoid and ulcerative colitis.
Bertilimumab is still the most important driver for Immune, but Immuno-Oncology is hot, and Immune’s efforts in bi-specific antibodies, an area where big pharma has been investing heavily over the past few years, could lead to significant value creation for investors as the development progresses. Earlier in the week, Immune further strengthened its efforts in Immuno-Oncology and bi-specific antibodies with the licensing of technology and patents from Atlante Biotech SAS, a privately-held European biotech company that was part of the aforementioned European consortium working with Immune lisan the initial bi-specific antibody prototype.
Tal Kadouche, a scientific co-founder of Immune Pharma. The technology in-licensed by Immune expands the company’s platform to target immune checkpoint inhibitors and will help listah company generate additional pre-clinical data with selected bi-specific drug candidates in Checkpoint Inhibitors – All The Rave An important part of the immune system is its ability to distinguish between normal cells ljstan foreign invaders.
This identification allows the immune system to attack and destroy foreign or malignant cells while leaving the normal cells alone. Cancer cells sometimes find ways to use these checkpoints to avoid being attacked ato the immune system. As such, drugs that target these checkpoints hold significant promise for the treatment of cancer. The drug is approved for the treatment of advanced melanoma. Both are also approved listaan advanced melanoma and a specific form of ,istan non-small cell lung cancer.
Beyond these three approved drugs, several other companies, including Roche and AstraZeneca, are working on immune checkpoint inhibitors targeting PD-1 and programmed death-ligand 1 PD-L1. It’s a novel strategy, but one that could pay off with significant dividends if successful. For example, only a few months ago the U.
These are two monoclonal antibodies targeting two different checkpoint inhibitors. Immune’s strategy with its bi-specific platform is to develop one antibody with two Fab fragments that might be able to accomplish what only combination therapy can ,istan today.
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Conclusion I think will be a pivotal year for Immune Pharma. Both Phase 2 clinical trials with Bertilimumab are enrolling patients, with data from the bullous pemphigoid trial likely in the second quarter of the year.
I’m also expecting that the company will provide an update on its Immune-Dermatology and NanomAbs programs in as outlined by Dr.
Teper’s shareholder letter released earlier in the month. Besvara 3 Visa diskussion. Och det bekommer mig inte en sekund att vi ev.