Asam Folat Merupakan Senyawa Induk Dari Sekumpulan Senyawa Yang Secara Umum Kajian Aktivitas Asam Usnat Terhadap Bakteri Penyebab Bau Badan. Laporan Asam Usnat A7. Cargado por. Muflihatun Khoeriyah · Cargado por. Muflihatun Khoeriyah · Cargado por. Muflihatun Khoeriyah. Asam usnat merupakan kandungan kimia dari Usnea barbata. Pada isolasi asam usnat, pertama kali sampel dihaluskan untuk memperbesar luas permukaan.
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Usnic acid is a naturally occurring dibenzofuran derivative found in several lichen species with the formula C 18 H 16 O 7. It was first isolated by German scientist W. Knop in  and first synthesized between by Curd and Robertson. Although it is generally believed that usnic acid is exclusively restricted to lichens, in a few unconfirmed isolated cases usnta compound was found in kombucha tea and non-lichenized ascomycetes.
At normal conditions, usnic acid is a bitter, yellow, solid substance. Salts of usnic acid are called usnates e. Usnic acid is a secondary metabolite in lichens whose role has not been completely elucidated. It is believed that usnic acid protects the lichen from adverse effects of sunlight exposure and deters grazing animals with its bitter taste. Lichen extracts containing usnic acid have been used in medicine, perfumery, cosmetics, and usnag.
Usnic acid possesses a wide range of biological properties. It is a potent antibiotic effective against Gram-positive bacteria, including StaphylococcusStreptococcusand Pneumococcusother bacteria such as Mycobacterium tuberculosisand some pathogenic fungi. Usnic acid has been included as an ingredient in creams, powders, toothpastes, mouthwash, deodorants, hair shampoos and sunscreen products. In some of these preparations, usnic acid is employed as an active principle, in others as a preservative.
Usnic acid and its salt form, sodium usniate, have been marketed in the US as an ingredient in food supplements for use in weight reduction, although this effect is unsupported by scientific evidence.
Asam usnat pdf
Usnic acid and its salts are idiosyncratically associated with asa hepatotoxicity and liver failure. Sodium usniate was one ingredient in a product called “Lipokinetix”, that saam claimed to induce weight loss via an increase in metabolic zsam. Lipokinetix has been the topic of an FDA warning in the USA,  due to potential hepatotoxicity, although it is unclear yet if any toxicity would be attributable to the aforementioned salt.
Lipokinetix also contained norephedrine PPAcaffeineyohimbine and 3,5-diiodothyronine. Usnic acid has been found to have adrenergic activity in both frog and earthworm nerve junction models in preliminary research. It is possible to determine the content of usnic acid in lichen extract using reversed-polarity capillary zone electrophoretic analysis.
From Wikipedia, the free encyclopedia. This section with questionable factual accuracy needs more medical references for verification or relies too heavily on primary sources.
Usnic acid – Wikipedia
Please review the contents of the section and add the appropriate references if you can. Unsourced or poorly sourced material may be challenged and removed. Retrieved 5 August Usnetol, usnetic acid, and pyrousnic acid”. Canadian Journal of Gastroenterology. Severe hepatotoxicity associated with use of a dietary supplement containing usnic acid.
Food and Drug Administration.
Retrieved 5 December FDA has received multiple reports of persons who developed liver injury or liver failure while using Lipokinetix. The product contains norephedrine also known as phenylpropanolamine or PPAcaffeine, yohimbine, diiodothyronine, and sodium usniate.
Reversed-polarity capillary zone electrophoretic analysis of usnic acid. Retrieved from ” https: Views Read Edit View history. In other projects Wikimedia Commons.